Figure 312

Causes of high-efficiency dialysis failure. The maintenance of a high blood flow rate (>350 mL/min) is essential for high-efficiency hemodialysis. Fistula recirculation, regardless of the blood flow rate, compromises achievement of the urea Kt/V goal. Interruptions during the prescribed short treatment time further compromise the overall delivery of the prescribed Kt/V [6,7]. K—urea clearance; t—time of therapy; V—volume of distribution.

Higher clearance of small solutes, such as urea, compared with conventional dialysis without increase in treatment time Better control of chemistry Potentially reduced morbidity Potentially higher patient survival rates

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