Figure 313

Hemoglobin and platelet values within 30 days of diagnosis of primary systemic amyloidosis. Anemia was not a prominent feature. When present, it usually is due to multiple myeloma, renal insufficiency, or gastrointestinal bleeding. Thrombocytosis was relatively common; in 9% of patients the platelet count was over 500 X 109/L. Functional hyposplenism from amyloid replacement of the spleen may occur [8]. Hyposplenism is manifested by the presence of Howell-Jolly bodies and occurs in about one fourth of patients. (Adapted from Kyle and Gertz [5].)

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