Figure 39

Technical requirements for high-efficiency dialysis. The KoA is the theoretic value of the urea clearance rate under conditions of infinite blood and dialysate flow. High blood and dialysate flow rates are necessary to achieve optimal performance of high-efficiency dialyzers. Bicarbonate-containing dialysate is necessary to prevent symptoms associated with acetate intolerance (ie, nausea, vomiting, headache, and hypotension), worsening of metabolic acidosis, and cardiac arrhythmia [6,8,9]. Ko—mass transfer coefficient; A—surface area.

Dialysate

Concentration

Sodium

139-145 mEq/L

Potassium

0-4 mEq/L

Acetate

2.5-4.5 mEq/L

Bicarbonate

35-40 mEq/L

Magnesium

1 mEq/L

Calcium

2.5-3.5 mEq/L

Glucose

0-200 mg/dL

0 0

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