Figure 44

Solute removal. The rates of change of solute concentrations are similar for 1.5% dextrose dialysis solutions (panel A) and 4.25% dextrose dialysis solutions (panel B). Hypertonic exchanges enhance solute removal owing to larger drain volumes. Net solute diffusion ceases at equilibration when the dialysate to plasma solute ratio (D/P)

is near 1.0. Smaller size solutes (ie, urea and creatinine) diffuse across the membrane faster, equilibrate sooner, and are influenced more by exchange frequency as compared with larger size solutes (ie, uric acid, phosphates, inulin, and proteins). (From Nolph and coworkers [10]; with permission.)

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