Figure 49

Equation to correct the creatinine levels in dialysate and serum. The creatinine levels in dialysate and serum need to be corrected for high glucose levels, which contribute to formation of noncreatinine chromogens during the creatinine assay. The correction factor may vary from one laboratory to another. In our laboratory at the University of Missouri-Columbia, the correction factor is 0.000531415. Accordingly, the corrected creatinine is calculated as in the equation. The correction in the serum is minimal due to low blood sugar levels; however, it is significant in dialysate, especially during the early phase of dwell (0- and 2-hour dialysate samples).

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