Figure 611

Effect of renal vein constriction on glomerular protein filtration. The role of angiotensin II (AII) in modulating macromolecular clearance across the glomerular capillary wall has been examined by Yoshioka and coworkers [11]. These authors used a model of renal vein constriction to increase glomerular pressure and markedly increase protein filtration. They calculated the volume flux through the small selective pores (effective pore radius, 40-50 A) within the glomerular capillary wall and through the large nonselective pores. A, Volume fluxes under control conditions (hatched bars) and during renal vein

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