Figure 62

Imaginary autoregulation curves in normal and diseased kidneys. Plotted on the y-axis are renal plasma flow (RPF), glomerular filtration rate (GFR), and glomerular capillary hydraulic pressure (Pqc) with undefined units. Ordinarily, RPF, GFR, and Pqc remain relatively constant over a wide range of perfusion pressures within the physiologic range, from approximately 80 to 140 mm Hg. Because autoregulatory ability is impaired in the kidneys of persons with chronic renal disease, these patients who develop systemic hypertension also are likely to have glomerular hypertension.

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