Figure 624

The broad lines of the immune response to parasitic infections. Note the pivotal role of the monocyte, activated by exposure to parasitic antigens, in stimulating both T-helper 1 (TH1) and T-helper 2 (TH2) cells. The different cytokine mediators and parasite elimination mechanisms are shown. B—B-lympho-cyte; 7-IFN—■y-interferon; CIC—circulating immune complexes; GM-CSF—granulocyte-macrophage colony-stimulating factor; Ig—immunoglobulin; IL—interleukin.

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