Figure 631

Study of patients with renal disease not associated with diabetes randomly assigned to ramipril or placebo. A study structured similarly to that in Figure 6-30 examined the use of the angiotensin-converting enzyme inhibitor ramipril in over 150 patients with nondiabetic renal disease [41]. The primary conclusion of the study is summarized. Blood pressure and proteinuria decreased more significantly in the patients treated with ramipril. This group had significantly lower rates of decline in glomerular filtration rate (GFR) over time. This effect was increasingly striking as the baseline level of proteinuria increased and was most pronounced in patients with a urinary protein excretion of over 7 g per 24 hours.

Favors ACE Inhibitors Favors other drugs

Reference

Country Year

Patie

Zucchelli et al. [43]

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