Figure 631

Pathogenesis of metabolic alkalosis. Two crucial questions must be answered when evaluating the pathogenesis of a case of metabolic alkalosis. 1) What is the source of the excess alkali? Answering this question addresses the primary event responsible for generating the hyperbicarbonatemia. 2) What factors perpetuate the hyperbicarbon-atemia? Answering this question addresses the pathophysiologic events that maintain the metabolic alkalosis.

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