Figure 711

Appropriate antibiotics for urinary tract infections (UTI). An appropriate antibiotic for treating UTI must be bactericidal and conform to the following general specifications: 1) its pharmacology must include, in case of oral administration, rapid absorption and attainment of peak serum concentrations; 2) its excretion must be predominantly renal; 3) it must achieve high concentrations in the renal or prostate tissue; 4) it must cover the usual spectrum of enterobacteria with reasonable chance of being effective on an empirical basis. Excluding special considerations for childhood and pregnancy, several classes of antibiotics fulfill these specifications and can be used alone or in combination. The choice also depends on market availability, cost, patient tolerance, and potential for inducing emergence of resistant strains.

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