Figure 711

Hemodynamic changes associated with ^-adrenergic blockade. Time course of hemodynamic changes after treatment with a ^-adrenergic blocker devoid of partial agonist activ ity (PAA) (solid line) as compared with hemodynamic changes after administration of a ^-adrenergic blocker with sufficient PAA to replace basal sympathetic tone (eg, pindolol) (broken line). MAP—mean arterial pressure. (From Man in't Veld and Schalekamp [10]; with permission.)

A. DOSING SCHEDULES FOR (-ADRENERGIC ANTAGONISTS: NON-SELECTIVE AND (2) ADRENERGIC ANTAGONISTS THAT LACK PARTIAL AGONIST ACTIVITY

Generic (trade) name

First dose, mg

Usual daily dose, mg

Maximum daily dose, mg

Duration of action, h

Nadolol (G)

0 0

Post a comment