Figure

Cellular model for renal tubular reabsorption of phosphorus in the proximal tubule. Phosphate reabsorption from the tubular fluid is sodium gradient-dependent and is mediated by the sodium gradient-dependent phosphate transport (Na-P( cotransport) protein located on the apical brush border membrane. The sodium gradient for phosphate reabsorption is generated by then sodium-potassium adenosine triphosphatase (Na-K ATPase) pump located on the basolateral membrane. Recent studies indicate that the Na-P( cotransport system is electrogenic [8,11]. ADP—adenosine diphosphate; An—anion.

Cellular model of proximal tubule P.-reabsorption

Blood

Parathyroid hormone dietary P( content

Parathyroid hormone dietary P( content hpo;

hpo;

3Na+

3Na+

Na+

0 0

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