Figure 82

Nomenclature of human leukocyte antigen (HLA) specificities. HLA nomenclature may be confusing to the newcomer, but the format is logical. The prefix HLA precedes all antigens or alleles to define the major histocompatibility complex (MHC) of the species. The designation, A, B, C, DR, and so on, is next and defines the locus. The locus is followed by a number that denotes the serologically defined antigen or a number with an asterisk that denotes the molecularly defined allele. In some cases the letter w is placed before the serologic antigen, indicating it is a workshop designation and the specific assignment is provisional.

Locus

Corresponding antigen

Specific allele

HLA phenotype

Patient cells tested with known antisera HLA antibody screen

Known cells tested with patient sera HLA crossmatch Donor cells tested with patient sera

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