Figure 831

Outcome of acute renal failure (ARF). Two groups of factors play a role on ARF outcome. The first includes factors that affect the patient: 1) previous health condition; 2) initial disease—usually, the direct or indirect (eg, treatments) cause of kidney failure; 3) the kind and severity of kidney injury. While 1 is a conditioning element, 2 and 3 trigger the second group of factors: the response of the patient to the insult. If this response includes a systemic inflammatory response syndrome (SIRS) like that usually seen in intensive care patients (eg, sepsis, pancreatitis, burns), a multiple organ dysfunction syndrome (MODS) frequently appears and consequently outcome is associated with a higher fatality rate (thick line). On the contrary, if SIRS does not develop and isolated ARF predominates, death (thin line, right) is less frequent than survival (thick line).

0 0

Post a comment