Figure 918

Interstitial infiltrates having different degrees of intensity and diffusion. When present, these infiltrates are composed not only of T lymphocytes and monocyte macrophages, as in most glomerular diseases, but also of B lymphocytes. (Periodic acid-Schiff reaction X 100.)

FIGURE 9-19 (see Color Plate)

Arteritis of small and medium-sized arteries. In about one third of cases an arteritis of small and medium-size arteries also is present. The artery shows diffuse fibrinoid necrosis of the vessel wall (in red) and intraparietal and perivascular leukocyte infiltration. It is worth emphasizing that even in the presence of renal arteritis we have never found in patients with cryoglobulinemia a picture of necrotizing crescentic glomerulonephritis, now considered a specific aspect of capillaritis in primary vasculitis (antineutrophil cytoplasm antibody-associated). This finding suggets that the vasculitic damage is limited to arterial vessels of larger size. (Trichrome X 100.)

Renal syndrome

Patients, %

Frequent histologic features

Isolated proteinuria with microscopic hema

0 0

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