Figure 928

Autosomal-dominant polycystic kidney disease (ADPKD): ultrasonographic diagnostic criteria. Ultrasound diagnostic criteria for the PKD1 form of ADPKD, as established by Ravine's group on the basis of both a sensitivity and specificity study [4, 28]. Note that the absence of cyst before age 30 years does not rule out the diagnosis, the false-negative rate being inversely related to age. When ultrasound diagnosis remains equivocal, the next step should be either contrast-enhanced CT (more sensitive than ultrasonography in the detection of small cysts) or gene linkage (see Figure 9-29). A similar assessment is not yet available for the PKD2 form. (From Ravine et al. [28]; with permission.)

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