Future Directions

HUMAN IGF-I IN PATIENTS WITH ARF*

Multicenter, doubleblind, randomized, placebo-controlled

*No difference between the groups were observed in final values or changes in values for glomerular filtration

1 Hour

1 Day

2 Days

5 Days

References

ARF secondary to surgery, trauma, hypertensive nephropathy, sepsis, or drugs Treated within the first 6 days for 14 days

Evaluated renal function and mortality t t t t t t (6 h) l (6 h)

Bardella et al [5] Ouellette et ai [6] Bonventre et al. [7] Witzgall et al [8]

Soifer et al [12] Firth and Ratcliffe [13]

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