Water Deprivation

Vasopressin (AVP)

Osmolality with

Abrupt onset


(mOsm/kg H2O)

after Dehydration

Exogenous AVP

Equal frequency in both sexes


> 800

> 2 pg/mL

Little or none

Rare in infancy, usual in second decade of life

Complete central

< 300



Predilection for cold water

diabetes insipidus

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