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FIGURE 9-17 (see Color Plate)

FIGURE 9-17 (see Color Plate)

The pattern of immunohistologic glomerular staining varies according to the different glomerular patterns seen on light microscopy. A, Diffuse granular subendothelial deposits along the capillary walls, with or without very rare intraluminal thrombi. (Immunoglobulin M X 250). B, Intense massive staining of the deposits totally filling the capillary lumina. Faint and irregular parietal deposits also are present. (Immunoglobulin X 250.) C, Parietal deposits with more evident peripheral lobular distribution. (Immunoglobulin X 250.) The components of mixed cryo-globulinemia immunoglobulin M and G, usually associated with C3, are the most frequently found immunoreactants.

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