Renal Disease Associated With Systemic Illness

Pregnancy and SLE*

Antiphospholipid antibody syndrome in pregnancy

Poor outcome is associated with the following:

Increased fetal loss

Active disease at conception

Arterial and venous thromboses

Disease first appearing during pregnancy

Renal vasculitis, thrombotic microangiopathy

Hypertension, azotemia in the first trimester

Preeclampsia

High titers of antiphospholipid antibodies or

Treatment: heparin and aspirin?

lupus anticoagulant

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