Major advantages of tacrolimus

Major disadvantages of tacrolimus

Steroid sparing

Increased viral infections

Less hypertension


Rescue of cyclosporine-resistant

Epstein-Barr virus


Increased lymphoproliferative disease

Minor advantages of tacrolimus

Minor disadvantages of tacrolimus

Better graft survival

Increased acute rejection?

Less hirsutism

More diabetogenic?

Less gingival hypertrophy


Less neurologic dysfunction


Less metabolic acidosis

Similarities of tacrolimus and

Less hyperlipidemia


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