Tgfr

Saralasin

Toxic, ischemic

Before

TRBF; no change in Scr, BUN

Captopril

Toxic, ischemic

Before

TRBF; no change in Scr, BUN

Verapamil

Ischemic, toxic

Before, during, after

TRBF, GFR in most studies

Nifedipine

Ischemic

Before

Tgfr

Nitrendipine

Toxic

Before, during

Tgfr

Diliazem

Toxic

Before, during, after

TGFR; ¿recovery time

Chlorpromazine

Toxic

Before

TGFR; ¿recovery time

Atrial natriuretic

Ischemic, toxic

After

TRBF, GFR

peptide peptide

BUN—blood urea nitrogen; GFR—glomerular filtration rate; RBF—renal blood flow; Scr-serum creatinine.

B. VASODILATORS USED TO ALTER COURSE OF CLINICAL ACUTE RENAL FAILURE (ARF)

Vasodilator

ARF Disorder

Observed Effect

Remarks

Dopamine

Ischemic, toxic

Improved V, Scr if used early

Combined with furosemide

Phenoxybenzamine

Ischemic, toxic

No change in V, RBF

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