Treatment Of Hyperphosphatemia

Consequences of secondary changes in calcium, parathyroid hormone, vitamin D metabolism and hypocalcemia:

Neuromuscular irritability Tetany Hypotension Increased QT interval

Consequences of ectopic calcification:

Periarticular and soft tissue calcification

Vascular calcification

Ocular calcification

Conduction abnormalities

Pruritus

Acute hyperphosphatemia in Chronic hyperphosphatemia in patients with adequate renal patients with end-stage renal function disease

Saline diuresis that causes phosphaturia Dietary phosphate restriction

Phosphate binders to decrease gastrointestinal phosphate reabsorption

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