Conjugated estrogens, mitomycin, quinine

* Many other drugs in addition to the ones listed can cause renal failure by this mechanism. t Interleukin-2 produces a capillary leak syndrome with volume contractions. ยง Uric acid crystals form as a result of tumor lysis. ^ The mechanism of this agent is unclear but may be due to additives.

** Acute renal failure is most likely to occur when lovastatin is given in combination with cyclosporine. *** Ethylene glycol-induced toxicity can cause calcium oxalate crystals.

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