Thrombotic Microangiopathy

FIGURE 10-19

Thrombotic microangiopathy in renal allografts. A host of different conditions and influences can lead to arteriolar and capillary thrombosis in renal allografts and these are as various as the first dose reaction to OKT3, HIV infection, episodes of cyclosporine toxicity, and antibody-mediated rejection [2, 12, 13]. It is hoped that further study will allow for more accurate diagnosis in patients manifesting this lesion. The figure shows arteriolar thrombosis and ischemic capillary collapse in a case of transplant thrombotic microangiopathy.

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