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As an antiarrhythmic drug, tocainide is most similar in action to which one of the following agents 10. Which of the following antiarrhythmic agents is (are) associated with an adverse effect known as cinchonism 11. Which of the following are employed clinically as intranasal steroids II. fluticasone propionate (Flonase) III. nedocromil (Tilade) 12. Which of the following agents is (are) used as anorexiants II. mazindol (Sanorex, Mazanor) III. benzphetamine (Didrex) 13. Colestipol HC1...

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Which of the following drugs is (are) sulfonamides 135. Which of the following drugs may be used in the treatment of diabetes insipidus 136. In the treatment of cardiac arrhythmias, Sotalol (Betapace) is most similar in action to 137. The sulfonylureas (eg, Diabinese, Glucotrol) are believed to exert their hypoglycemic effect by (A) stimulating the release of insulin from the pancreas (B) inhibiting the breakdown of endogenous insulin (C) decreasing the absorption of dietary glucose (D)...

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Moiety present since some official chemical designations do not indicate 100 pure chemical. For example, waters of hydration, a certain amount of moisture, or other impurities must be taken into consideration. (4 12.4 19 4) x 181.8 grams of anhydrous theophylline Since the anhydrous theophylline has 0.4 unbound water, it is only 99.6 pure. Qil Q Q2 C2 181.8 g 100 x g 99.6 While the differences between 184.5 and 181.1 or 181.8 do not appear significant, the principle of correcting for either...

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27. (C) Urinary excretion studies require complete urine collection so that the total quantity of drug that is excreted in the urine can be determined. Normal or near-normal renal function is also a prerequisite for accurate urinary excretion studies because sufficiently impaired renal function can alter the composition of various body fluids that, in turn, can alter the pharmacokinetic properties of many drugs. Although urinary excretion studies are usually conducted on drugs that are...

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Lansoprazole (Prevacid) inhibits gastric acid secretion as a result of 42. A patient complains about a headache that is localized in the periorbital area and seems to be worse in the morning than in the after- noon. Which of the following would be the best way to characterize the headache 43. The purpose of combination drug treatment in tuberculosis is to I. increase the tuberculostatic effects of the drugs II. delay the emergence of drug resistance III. reduce the duration of therapy 44....

Sodium Chloride And Staph Infection

Advantages to the manufacturer for tablet film coating when compared to sugar coating include I. shorter production times II. less gross weight III. lower incidence in coat chipping 118. Which one of the following statements concerning bisacodyl is NOT true (A) Laxative action occurs within 6 hours after oral administration. (B) Action of the suppositories occurs within 1 hour of insertion. (C) Suppositories may cause rectal irritation with continued administration. (D) Tablets should be...

Maximum Volume Allowed As A Parenteral Package For Bacteriostatic Injection

Which one of the following parenteral antibiotics is the most stable in an aqueous solution 65. Methylparaben is an ester of 66. Which of the descriptions of Pharmacy Bulk Packages is (are) true I. units intended for preparation of sterile parenterals II. do not have an antimicrobial preservative III. may be used for direct infusion of drugs into patients 67. Parenteral containers of potassium chloride concentrate must be packaged (B) in vials not greater than 20 mL capacity (C) in vials...

Apa Itu Chlorade Rr

How many mg of codeine base is in each dose of the cough product used in Question 11 (Mol. wts codeine 299 codeine phosphate 406) 13. The directions intended for the patient on a prescription read 1 tbsp ac and hs for 10 days. What is the minimum volume the pharmacist should dispense 14. The USP contains nomograms for estimating body surface area (BSA) for both children and adults. Which of the following measurements must be known in order to use this nomogram height and creatinine...

Progesterone 20mg Peg 400 60 Peg 6000

The ideal weight for a vaginal suppository will be approximately 57. Which of the following suppository bases melt rather than dissolve when inserted into the rectum Progesterone 20 mg PEG 400 60 PEG 6000 40 55. Which of the following statements is are true with respect to the previously shown formula I. The weight of the individual suppository must be determined experimentally. II. It is necessary to prepare the formula suppositories using a mold. III. The volume density of the progesterone...

Benzalkonium Chloride Is Rentered Inactive In Presence Of

Which one of the following chemicals is NOT suitable as a drug excipient 16. Which of the following chemicals may be included in a drug solution as a chelating agent 17. Which of the following ions may be effectively chelated by EDTA 18. Although most drugs in pharmaceutical dosage forms are expected to decompose following first-order kinetics, an exception are drugs formulated in 19. An early sign of a decomposing epinephrine 20. On exposure to air, aminophylline solutions may develop C a...