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Which of the following drugs is (are) sulfonamides 135. Which of the following drugs may be used in the treatment of diabetes insipidus 136. In the treatment of cardiac arrhythmias, Sotalol (Betapace) is most similar in action to 137. The sulfonylureas (eg, Diabinese, Glucotrol) are believed to exert their hypoglycemic effect by (A) stimulating the release of insulin from the pancreas (B) inhibiting the breakdown of endogenous insulin (C) decreasing the absorption of dietary glucose (D)...

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Which of the following beta-adrenergic blocking agents is betaj-selective I. betaxolol (Betoptic) II. metipranolol HC1 (OptiPranolol) III. timolol (Timoptic) 109. Which of the following is true of pilocarpine (Isopto Carpine, Pilostat) I. similar pharmacologic action to dorzol- amide (Trusopt) II. direct-acting mydriatic III. ingredient in Ocusert ocular therapeutic system 111. Which one of the following statements best describes the mechanism of action of ranitidine (Zantac) (A) It...

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Moiety present since some official chemical designations do not indicate 100 pure chemical. For example, waters of hydration, a certain amount of moisture, or other impurities must be taken into consideration. (4 12.4 19 4) x 181.8 grams of anhydrous theophylline Since the anhydrous theophylline has 0.4 unbound water, it is only 99.6 pure. Qil Q Q2 C2 181.8 g 100 x g 99.6 While the differences between 184.5 and 181.1 or 181.8 do not appear significant, the principle of correcting for either...

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27. (C) Urinary excretion studies require complete urine collection so that the total quantity of drug that is excreted in the urine can be determined. Normal or near-normal renal function is also a prerequisite for accurate urinary excretion studies because sufficiently impaired renal function can alter the composition of various body fluids that, in turn, can alter the pharmacokinetic properties of many drugs. Although urinary excretion studies are usually conducted on drugs that are...

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Lansoprazole (Prevacid) inhibits gastric acid secretion as a result of 42. A patient complains about a headache that is localized in the periorbital area and seems to be worse in the morning than in the after- noon. Which of the following would be the best way to characterize the headache 43. The purpose of combination drug treatment in tuberculosis is to I. increase the tuberculostatic effects of the drugs II. delay the emergence of drug resistance III. reduce the duration of therapy 44....

Sodium Chloride And Staph Infection

Advantages to the manufacturer for tablet film coating when compared to sugar coating include I. shorter production times II. less gross weight III. lower incidence in coat chipping 118. Which one of the following statements concerning bisacodyl is NOT true (A) Laxative action occurs within 6 hours after oral administration. (B) Action of the suppositories occurs within 1 hour of insertion. (C) Suppositories may cause rectal irritation with continued administration. (D) Tablets should be...

Maximum Volume Allowed As A Parenteral Package For Bacteriostatic Injection

Which one of the following parenteral antibiotics is the most stable in an aqueous solution 65. Methylparaben is an ester of 66. Which of the descriptions of Pharmacy Bulk Packages is (are) true I. units intended for preparation of sterile parenterals II. do not have an antimicrobial preservative III. may be used for direct infusion of drugs into patients 67. Parenteral containers of potassium chloride concentrate must be packaged (B) in vials not greater than 20 mL capacity (C) in vials...

Progesterone 20mg Peg 400 60 Peg 6000

The ideal weight for a vaginal suppository will be approximately 57. Which of the following suppository bases melt rather than dissolve when inserted into the rectum Progesterone 20 mg PEG 400 60 PEG 6000 40 55. Which of the following statements is are true with respect to the previously shown formula I. The weight of the individual suppository must be determined experimentally. II. It is necessary to prepare the formula suppositories using a mold. III. The volume density of the progesterone...