Early Ossification of the Femoral Head

► [Premature ossification of the femoral capital epiphysis)

In normal children, the ossific nucleus of the femoral head appears between 2 and 8 months of age. Ossification occurs earlier in girls than in boys, since skeletal maturation is more advanced in girls than in boys at all ages. The presence of calcific deposits within the secondary nucleus of the femoral head at birth is rare, being found in asphyxiating thoracic dysplasia and Ellis-van Creveld syndrome.

In neonates with asphyxiating thoracic dysplasia (Jeune syndrome, OMIM 208500), premature ossification of the femoral capital epiphyses occurs in association with horizontal showing a characteristic acetabuli 'trident' appearance, squared iliac bones with round lateral borders, short pubic and ischial bones, and small sciatic notches. These features tend to improve over time (Oberklaid et al. 1977). Chondroectodermal dysplasia (Ellis-van Creveld syndrome, OMIM 225500) has overlapping features (Kozlowski et al. 1972).

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