In 1963, Williams and Sandler classified carcinoids according to their embryologic site of origin.9 They proposed that tumors be classified into foregut

Figure 18-1. Enterochromaffin cell (brown signal) from normal antral mucosa (blue coloi) with staining for chromogranin A (chromo-granin immunoperoxidase; x400 original magnification). Courtesy of L. Antunes, MD, PhD, Department of Pathology, Nancy, France.

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