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Thyroid Factor

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* RET/PTC NTRK1 met

Figure 2-2. Proposed multistep tumorigenesis in differentiated thyroid carcinomas. 'Oncogene activation; +tumor suppressor gene inactivation.

* RET/PTC NTRK1 met

Figure 2-2. Proposed multistep tumorigenesis in differentiated thyroid carcinomas. 'Oncogene activation; +tumor suppressor gene inactivation.

cally euthyroid and have normal serum thyrotropin (thyroid-stimulating hormone [TSH]) concentrations.10 The most cost-effective method for diagnosing malignant thyroid nodules is by fine-needle aspiration biopsy (FNAB). FNAB is reliable in identifying PTC (Figure 2-3); however, it does not distinguish FTC

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