Interactions Between the Lymphatic and Immune Systems and Other Organ Systems

indicates ways in which these systems affect other organ systems indicates ways in which other organ systems affect these systems

Nearly All Systems

Lymphatic system drains excess tissue fluid and removes cellular debris and pathogens. Immune system provides defense against pathogens and immune surveillance against cancer.

Integumentary System

^^ Skin provides mechanical and chemical barriers to pathogens; has antigen-presenting cells in epidermis and dermis; and is a common site of inflammation

Skeletal System

^^ Lymphocytes and macrophages arise from bone marrow cells; skeleton protects thymus and spleen

Muscular System

^- Skeletal muscle pump moves lymph through lymphatic vessels Nervous System

^^ Neuropeptides and emotional states affect immune function; blood-brain barrier prevents antibodies and immune cells from entering brain tissue

Endocrine System

Lymph transports some hormones ^- Hormones from thymus stimulate development of lymphatic organs and T cells; stress hormones depress immunity and increase susceptibility to infection and cancer

Circulatory System

Cardiovascular system would soon fail without return of fluid and protein by lymphatic system; spleen disposes of expired erythrocytes and recycles iron; lymphatic organs prevent accumulation of debris and pathogens in blood ^^ Lymphatic vessels develop from embryonic veins; arterial pulsation aids flow of lymph in neighboring lymphatic vessels; leukocytes serve in nonspecific and specific defense; blood transports immune cells, antibodies, complement, interferon, and other immune chemicals; capillary endothelial cells signal areas of tissue injury and stimulate margination and diapedesis of leukocytes; blood clotting restricts spread of pathogens

Respiratory System

Alveolar macrophages remove debris from lungs ^^ Provides immune system with O2; disposes of CO2; thoracic pump aids lymph flow; pharynx houses tonsils

Urinary System Interactions

Urinary System

Absorbs fluid and proteins in kidneys, which is essential to enabling kidneys to concentrate the urine and conserve water ^^ Eliminates waste and maintains fluid and electrolyte balance important to lymphatic and immune function; urine flushes some pathogens from body; acidic pH of urine protects against urinary tract infection

Digestive System

Lymph absorbs and transports digested lipids ^^ Nourishes lymphatic system and affects lymph composition; stomach acid destroys ingested pathogens

Reproductive System

Immune system requires that the testes have a blood-testis barrier to prevent autoimmune destruction of sperm ^^ Vaginal acidity inhibits growth of pathogens

Saladin: Anatomy & I 21. The Lymphatic and I Text I © The McGraw-Hill

Physiology: The Unity of Immune System Companies, 2003 Form and Function, Third Edition

Chapter 21 The Lymphatic and Immune Systems 835

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  • michael
    How does the lymphatic sytem interact with other body sytems?
    8 months ago
  • naomi
    How does the digestive system and the integumentary system have interactions?
    2 months ago

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